2019 Inquiry Capstone Presentations
On Monday 5/20, Wednesday 5/22, and Thursday 5/23, SLA seniors will be presenting their inquiry capstone projects. The schedule for capstone presentations can be found here.
Good luck, seniors!
On Monday 5/20, Wednesday 5/22, and Thursday 5/23, SLA seniors will be presenting their inquiry capstone projects. The schedule for capstone presentations can be found here.
Good luck, seniors!
On Tuesday 5/29, Wednesday 5/30, and Thursday 5/31, SLA seniors will be presenting their capstone projects. The schedule for capstone presentations can be found here.
Good luck, seniors!
The science behind prenatal diagnosis
Prenatal diagnosis is the screening or testing for genetic diseases or other conditions before a child is born. Although there are many different techniques and tests, I will focus on a few:
Societal Impacts
While the above techniques may sound like wonderful advances in medicine, they also have their downsides. First, there’s a difference between screening and testing. A prenatal genetic screen - like maternal blood testing - only gives the level of risk of a condition, but it can not with 100% certainty diagnose a condition. Prenatal genetic tests - like amniocentesis and CVS - are more diagnostic, but also have higher risks for the pregnancy. And if a non-invasive screen detects a high risk for Down Syndrome, for example, the parents are then faced with the decision of whether or not to do a more invasive, high risk test in order to more accurately determine whether Down Syndrome is present. If the results of a CVS or amniocentesis indicate a genetic disorder, then the couple could be faced with the decision to terminate the pregnancy. At the very least, these weeks of testing and waiting for results can be draining and extremely stressful. Pregnancy can already be a stressful time, and these prenatal screens and test can add to that anxiety.
On the other hand, some parents feel that they’d like to know the risks, regardless of the outcome of a test. If a screening test comes back positive for a genetic disorder, then the parents at least won’t be surprised at the birth. They’ll have time to prepare, educate themselves, and possibly arrange for special care that might be needed for their newborn.
Some people opt out of the screens and tests altogether. They might argue that what’s meant to be is meant to be, and they’d rather spare themselves the stress and anxiety surrounding these tests and their results.
And finally, with PGD it is possible to choose the sex of your child. This is illegal in some countries, including Canada - but not the US. Given that IVF and PGD could cost $15000-$20000, the opportunity to screen embryos for genetic conditions and possibly select the sex would not be affordable for everyone. Is this fair? Should people be allowed to choose the sex of their children?
Personal opinions
As someone who loves science, I’m fascinated by these medical advances, and support further research into tests and screens like these. It’s exciting when new, improved tests come out that can help people get answers to their pregnancy concerns, and hopefully allay some of their fears. However, it’s easy for me to support these tests in a general, abstract way. It becomes more complicated when we’re talking about real pregnancies in my personal life. I’ve gone through some of these discussions and decisions, and sometimes there is no easy answer. I can see why people would be in the “no testing” camp - the screenings and testing definitely can raise anxiety and stress levels during pregnancy, which can already be pretty stressful. Still, I’m glad the tests are available, and I think they should continue to be offered to pregnant women. Key to this though, is that they need to be able to make informed decisions. Through discussions with their doctor and a knowledgeable genetic counselor, the parents-to-be can weigh the pros and cons for themselves, and then decide how they want to handle the conundrum of prenatal genetic diagnosis.
References: Nierneberg, C. (2014). Prenatal Genetic Screening Tests: Benefits & Risks. Retrieved February 24, 2016, from http://www.livescience.com/45949-prenatal-genetic-testing.html
Sidhu, J. (n.d.). Women Are Paying Huge Sums To Have a Daughter Rather Than a Son. Retrieved February 24, 2016, from http://www.slate.com/articles/health_and_science/medical_examiner/2012/09/sex_selection_in_babies_through_pgd_americans_are_paying_to_have_daughters_rather_than_sons_.html
I wish I hadn’t known: The ups and downs of prenatal testing. (n.d.). Retrieved February 24, 2016, from http://www.pregnancyandbaby.com/pregnancy/articles/944203/i-wish-i-hadnt-known-the-ups-and-downs-of-prenatal-testing
The science behind prenatal diagnosis
Prenatal diagnosis is the screening or testing for genetic diseases or other conditions before a child is born. Although there are many different techniques and tests, I will focus on a few:
Societal Impacts
While the above techniques may sound like wonderful advances in medicine, they also have their downsides. First, there’s a difference between screening and testing. A prenatal genetic screen - like maternal blood testing - only gives the level of risk of a condition, but it can not with 100% certainty diagnose a condition. Prenatal genetic tests - like amniocentesis and CVS - are more diagnostic, but also have higher risks for the pregnancy. And if a non-invasive screen detects a high risk for Down Syndrome, for example, the parents are then faced with the decision of whether or not to do a more invasive, high risk test in order to more accurately determine whether Down Syndrome is present. If the results of a CVS or amniocentesis indicate a genetic disorder, then the couple could be faced with the decision to terminate the pregnancy. At the very least, these weeks of testing and waiting for results can be draining and extremely stressful. Pregnancy can already be a stressful time, and these prenatal screens and test can add to that anxiety.
On the other hand, some parents feel that they’d like to know the risks, regardless of the outcome of a test. If a screening test comes back positive for a genetic disorder, then the parents at least won’t be surprised at the birth. They’ll have time to prepare, educate themselves, and possibly arrange for special care that might be needed for their newborn.
Some people opt out of the screens and tests altogether. They might argue that what’s meant to be is meant to be, and they’d rather spare themselves the stress and anxiety surrounding these tests and their results.
And finally, with PGD it is possible to choose the sex of your child. This is illegal in some countries, including Canada - but not the US. Given that IVF and PGD could cost $15000-$20000, the opportunity to screen embryos for genetic conditions and possibly select the sex would not be affordable for everyone. Is this fair? Should people be allowed to choose the sex of their children?
Personal opinions
As someone who loves science, I’m fascinated by these medical advances, and support further research into tests and screens like these. It’s exciting when new, improved tests come out that can help people get answers to their pregnancy concerns, and hopefully allay some of their fears. However, it’s easy for me to support these tests in a general, abstract way. It becomes more complicated when we’re talking about real pregnancies in my personal life. I’ve gone through some of these discussions and decisions, and sometimes there is no easy answer. I can see why people would be in the “no testing” camp - the screenings and testing definitely can raise anxiety and stress levels during pregnancy, which can already be pretty stressful. Still, I’m glad the tests are available, and I think they should continue to be offered to pregnant women. Key to this though, is that they need to be able to make informed decisions. Through discussions with their doctor and a knowledgeable genetic counselor, the parents-to-be can weigh the pros and cons for themselves, and then decide how they want to handle the conundrum of prenatal genetic diagnosis.
References: Nierneberg, C. (2014). Prenatal Genetic Screening Tests: Benefits & Risks. Retrieved February 24, 2016, from http://www.livescience.com/45949-prenatal-genetic-testing.html
Sidhu, J. (n.d.). Women Are Paying Huge Sums To Have a Daughter Rather Than a Son. Retrieved February 24, 2016, from http://www.slate.com/articles/health_and_science/medical_examiner/2012/09/sex_selection_in_babies_through_pgd_americans_are_paying_to_have_daughters_rather_than_sons_.html
I wish I hadn’t known: The ups and downs of prenatal testing. (n.d.). Retrieved February 24, 2016, from http://www.pregnancyandbaby.com/pregnancy/articles/944203/i-wish-i-hadnt-known-the-ups-and-downs-of-prenatal-testing
Prenatal diagnosis is the screening or testing for genetic diseases or other conditions before a child is born. Although there are many different techniques and tests, I will focus on a few:
Preimplantation genetic diagnosis (PGD): During an IVF cycle, cells from the developing embryo can be genetically analyzed for chromosomal abnormalities - usually trisomy 21 (Down Syndrome), trisomy 13 and trisomy 18. The parents can then determine which embryos, if any, to transfer into the uterus. It is also possible to determine the sex of the embryo.
Ultrasound: An ultrasound uses sound waves to “look” at a fetus as it develops in the uterus. Since sound waves reflect off of tissues differently depending on the density of the tissue, the sonographer can create images of the fetus’ external and internal anatomy. Ultrasound can be used to measure an embryo or fetus in order to predict the due date, detect twins, diagnose heart and other growth defects, measure heart rate, look for signs associated with Down Syndrome, and determine the sex of the fetus.
Chorionic villus sampling: The chorionic villi are a part of the placenta that arises directly from the embryo (as opposed to the mother). They are, therefore, genetically identical to the developing embryo. Chorionic villi can be removed from the placenta and genetically analyzed to detect Down Syndrome and other genetic disorders. CVS has a slight risk (.5-1%) of miscarriage, and can also lead to amniotic fluid leakage and/or infection.
Amniocentesis: A fetus develops in the amniotic sac, which is full of amniotic fluid. The amniotic fluid contains fetal cells that have naturally sloughed off. The doctor, using an ultrasound image as a guide, inserts a needle through the mother’s skin, abdominal wall, uterine wall, and into the amniotic sac, away from the fetus. Amniotic fluid is then collected, and the fetal cells contained in the fluid can be analyzed for genetic conditions such as Down Syndrome. Amniocentesis has similar risks as CVS, although CVS can be done earlier.
Maternal Blood Testing: A relatively recently developed technique can detect fetal DNA in the mother’s blood stream. Thus, with a simple blood draw, the fetus’ sex can be determined, and it can be screened for a variety of genetic disorders.
Societal Impacts
While the above techniques may sound like wonderful advances in medicine, they also have their downsides. First, there’s a difference between screening and testing. A prenatal genetic screen - like maternal blood testing - only gives the level of risk of a condition, but it can not with 100% certainty diagnose a condition. Prenatal genetic tests - like amniocentesis and CVS - are more diagnostic, but also have higher risks for the pregnancy. And if a non-invasive screen detects a high risk for Down Syndrome, for example, the parents are then faced with the decision of whether or not to do a more invasive, high risk test in order to more accurately determine whether Down Syndrome is present. If the results of a CVS or amniocentesis indicate a genetic disorder, then the couple could be faced with the decision to terminate the pregnancy. At the very least, these weeks of testing and waiting for results can be draining and extremely stressful. Pregnancy can already be a stressful time, and these prenatal screens and test can add to that anxiety.
On the other hand, some parents feel that they’d like to know the risks, regardless of the outcome of a test. If a screening test comes back positive for a genetic disorder, then the parents at least won’t be surprised at the birth. They’ll have time to prepare, educate themselves, and possibly arrange for special care that might be needed for their newborn.
Some people opt out of the screens and tests altogether. They might argue that what’s meant to be is meant to be, and they’d rather spare themselves the stress and anxiety surrounding these tests and their results.
And finally, with PGD it is possible to choose the sex of your child. This is illegal in some countries, including Canada - but not the US. Given that IVF and PGD could cost $15000-$20000, the opportunity to screen embryos for genetic conditions and possibly select the sex would not be affordable for everyone. Is this fair? Should people be allowed to choose the sex of their children?
Personal opinions
As someone who loves science, I’m fascinated by these medical advances, and support further research into tests and screens like these. It’s exciting when new, improved tests come out that can help people get answers to their pregnancy concerns, and hopefully allay some of their fears. However, it’s easy for me to support these tests in a general, abstract way. It becomes more complicated when we’re talking about real pregnancies in my personal life. I’ve gone through some of these discussions and decisions, and sometimes there is no easy answer. I can see why people would be in the “no testing” camp - the screenings and testing definitely can raise anxiety and stress levels during pregnancy, which can already be pretty stressful. Still, I’m glad the tests are available, and I think they should continue to be offered to pregnant women. Key to this though, is that they need to be able to make informed decisions. Through discussions with their doctor and a knowledgeable genetic counselor, the parents-to-be can weigh the pros and cons for themselves, and then decide how they want to handle the conundrum of prenatal genetic diagnosis.
References:
Nierneberg, C. (2014). Prenatal Genetic Screening Tests: Benefits & Risks. Retrieved February 24, 2016, from http://www.livescience.com/45949-prenatal-genetic-testing.html
Sidhu, J. (n.d.). Women Are Paying Huge Sums To Have a Daughter Rather Than a Son. Retrieved February 24, 2016, from http://www.slate.com/articles/health_and_science/medical_examiner/2012/09/sex_selection_in_babies_through_pgd_americans_are_paying_to_have_daughters_rather_than_sons_.html
I wish I hadn't known: The ups and downs of prenatal testing. (n.d.). Retrieved February 24, 2016, from http://www.pregnancyandbaby.com/pregnancy/articles/944203/i-wish-i-hadnt-known-the-ups-and-downs-of-prenatal-testing
The science behind prenatal diagnosis
Prenatal diagnosis is the screening or testing for genetic diseases or other conditions before a child is born. Although there are many different techniques and tests, I will focus on a few:
Preimplantation genetic diagnosis (PGD): During an IVF cycle, cells from the developing embryo can be genetically analyzed for chromosomal abnormalities - usually trisomy 21 (Down Syndrome), trisomy 13 and trisomy 18. The parents can then determine which embryos, if any, to transfer into the uterus. It is also possible to determine the sex of the embryo.
Ultrasound: An ultrasound uses sound waves to “look” at a fetus as it develops in the uterus. Since sound waves reflect off of tissues differently depending on the density of the tissue, the sonographer can create images of the fetus’ external and internal anatomy. Ultrasound can be used to measure an embryo or fetus in order to predict the due date, detect twins, diagnose heart and other growth defects, measure heart rate, look for signs associated with Down Syndrome, and determine the sex of the fetus.
Chorionic villus sampling: The chorionic villi are a part of the placenta that arises directly from the embryo (as opposed to the mother). They are, therefore, genetically identical to the developing embryo. Chorionic villi can be removed from the placenta and genetically analyzed to detect Down Syndrome and other genetic disorders. CVS has a slight risk (.5-1%) of miscarriage, and can also lead to amniotic fluid leakage and/or infection.
Amniocentesis: A fetus develops in the amniotic sac, which is full of amniotic fluid. The amniotic fluid contains fetal cells that have naturally sloughed off. The doctor, using an ultrasound image as a guide, inserts a needle through the mother’s skin, abdominal wall, uterine wall, and into the amniotic sac, away from the fetus. Amniotic fluid is then collected, and the fetal cells contained in the fluid can be analyzed for genetic conditions such as Down Syndrome. Amniocentesis has similar risks as CVS, although CVS can be done earlier.
Maternal Blood Testing: A relatively recently developed technique can detect fetal DNA in the mother’s blood stream. Thus, with a simple blood draw, the fetus’ sex can be determined, and it can be screened for a variety of genetic disorders.
Societal Impacts
While the above techniques may sound like wonderful advances in medicine, they also have their downsides. First, there’s a difference between screening and testing. A prenatal genetic screen - like maternal blood testing - only gives the level of risk of a condition, but it can not with 100% certainty diagnose a condition. Prenatal genetic tests - like amniocentesis and CVS - are more diagnostic, but also have higher risks for the pregnancy. And if a non-invasive screen detects a high risk for Down Syndrome, for example, the parents are then faced with the decision of whether or not to do a more invasive, high risk test in order to more accurately determine whether Down Syndrome is present. If the results of a CVS or amniocentesis indicate a genetic disorder, then the couple could be faced with the decision to terminate the pregnancy. At the very least, these weeks of testing and waiting for results can be draining and extremely stressful. Pregnancy can already be a stressful time, and these prenatal screens and test can add to that anxiety.
On the other hand, some parents feel that they’d like to know the risks, regardless of the outcome of a test. If a screening test comes back positive for a genetic disorder, then the parents at least won’t be surprised at the birth. They’ll have time to prepare, educate themselves, and possibly arrange for special care that might be needed for their newborn.
Some people opt out of the screens and tests altogether. They might argue that what’s meant to be is meant to be, and they’d rather spare themselves the stress and anxiety surrounding these tests and their results.
And finally, with PGD it is possible to choose the sex of your child. This is illegal in some countries, including Canada - but not the US. Given that IVF and PGD could cost $15000-$20000, the opportunity to screen embryos for genetic conditions and possibly select the sex would not be affordable for everyone. Is this fair? Should people be allowed to choose the sex of their children?
Personal opinions
As someone who loves science, I’m fascinated by these medical advances, and support further research into tests and screens like these. It’s exciting when new, improved tests come out that can help people get answers to their pregnancy concerns, and hopefully allay some of their fears. However, it’s easy for me to support these tests in a general, abstract way. It becomes more complicated when we’re talking about real pregnancies in my personal life. I’ve gone through some of these discussions and decisions, and sometimes there is no easy answer. I can see why people would be in the “no testing” camp - the screenings and testing definitely can raise anxiety and stress levels during pregnancy, which can already be pretty stressful. Still, I’m glad the tests are available, and I think they should continue to be offered to pregnant women. Key to this though, is that they need to be able to make informed decisions. Through discussions with their doctor and a knowledgeable genetic counselor, the parents-to-be can weigh the pros and cons for themselves, and then decide how they want to handle the conundrum of prenatal genetic diagnosis.
References:
Nierneberg, C. (2014). Prenatal Genetic Screening Tests: Benefits & Risks. Retrieved February 24, 2016, from http://www.livescience.com/45949-prenatal-genetic-testing.html
Sidhu, J. (n.d.). Women Are Paying Huge Sums To Have a Daughter Rather Than a Son. Retrieved February 24, 2016, from http://www.slate.com/articles/health_and_science/medical_examiner/2012/09/sex_selection_in_babies_through_pgd_americans_are_paying_to_have_daughters_rather_than_sons_.html
I wish I hadn't known: The ups and downs of prenatal testing. (n.d.). Retrieved February 24, 2016, from http://www.pregnancyandbaby.com/pregnancy/articles/944203/i-wish-i-hadnt-known-the-ups-and-downs-of-prenatal-testing
SLA Junior Manna-Symone Middlebrooks returned to her second PJAS State Fair to present a project on a Local Pollutant's Effect on Dissolved-Oxygen Producing Algae. This earned her both a First Award and a $2000/semester Scholarship to the Pennsylvania State University!
Finally, Senior Jeff Kessler earned a total of five awards at this year's competition! Jeff's study of the ElectroMagnetic Fields Emitted by Cell Phones not only earned him a First Award, but he achieved a perfect score of 5.0 (an additional distinction earned by less than 2% of all participants)! At the Special Award Ceremony, Jeff was also recognized for three years of participation at both the Regional and State levels, and won one of five Oerlein Awards for Outstanding Senior High School Science Student.
In total, SLA took home 10 State-Level awards and over $16,150 in monetary prizes! Congrats to all SLA PJAS State Participants!
Tuna Macaroni Salad
Ingredients:
4 Brown Organic eggs
2 pouches of Ronzoni Pasta Portions: elbow
½ cup Miracle Whip Mayonnaise (vary to preference)
Lawry’s Season Salt (vary to preference)
Old Bay Seasoning (vary to preference)
2 cans of Chicken of the Sea Solid White: Albacore tuna
Procedure:
1. Boil 2 pouches of pasta in 1 quart of water for 5minutes.
2. Boil 4 brown eggs for 10 minutes.
3. Drain and serve pasta into a large bowl
4. Open, drain and serve 2 cans of tuna into large bowl with pasta
5. Apply about ½ a cup of mayonnaise into bowl and mix contents of the bowl thoroughly.
6. Add a moderate amount (2 teaspoons each) of Lawry’s Seasoning Salt and Old Bay seasoning and mix (continue to taste and add more season as seen fit).
7. Un-shell and dice eggs into bowl and mix one last time.
Analysis:
Based on the ingredients used to make my meal, about 60% of my meal is processed being made of processed tuna fish and mayonnaise.
My entire meal totaled in 315mg cholesterol. 3,230mg sodium, 33g fat, 600mg potassium, 128g carbs, 6g dietary fibers, 6g sugars, 46g protein, and 1,630mg calories. The amount of sodium in my meal could cause serious high blood pressure and other health risks and the amount of calories (1,630mg) in my meal is half of the suggested 2,400-calorie intake for women, so eating everyday would not be healthy. Also be reminded that this is all only in one serving.
All ingredients used in my meal were made and packed in the United States; ranging from Pennsylvania, Maryland, New Jersey California. The Chicken of the Sea Tuna Fish traveled the furthest being from San Diego, California. Only my eggs were organically grown.
This meal cost about $15. In comparison to fast food, my meal may be equal in health risk somewhat, but it is not a meal to be eaten regularly. Also my meal is a bit more expensive when buy ingredients as a whole. The USDA regulates these ingredients.
Self Reflection
Being a person who has never once questioned what is on the back, ingredients and nutrient labeling of her everyday boxed processed food, this unit in science and society has changed my view and importance in food in multiple ways. From the identifying of terms and ingredients, the creation and modification of said ingredients and how these process of modified and organic foods has drastically effected America economically and health wise.
The initial assignment of simply reading what the ingredients were on a meal I had recently eaten was only step one of opening my eyes to the food I consume. After a discussion in class about the definition and creditability of certain terms found on the labeling of boxed/canned foods, I learned that terms like “Low-Fat” and “Natural” are not USDA regulated meaning; any thing claimed to be any percent less fat (even if it’s only 1%) than it’s original form can be considered “low fat” without any higher authority confirmation. It was facts that like and many others that alone made me more conscious of the ingredients in our foods.
Step two in discovering the truth behind our food was actually watching the documentary movie, “Food Inc” which had a range of discussion topics. It talked about the treatments of both animals and workers, the process of making food, the cost of food and how it economically effects America, the health causes of genetically modified foods, the political aspects of the food system and overall how as consumers, we have a large role in the food system and are capable of changing it. My group in particular took the chapter, “Shocks to the System” which discussed how an consumers, we are becoming slightly more conscious of the products/produce we purchase and this is partially due to the price inflammation and comparison of organic verses genetically modified. Stores like Wal-Mart have even gone “Green” in order to comply with costumers and appeal to high-class costumers who have begun to notice the difference between organic and genetically modified.
Step 3 was taking what I’ve
learned and applying it into my life by creating a meal that was ideally
healthy and free of genetically modified ingredients (homemade being the main
objective). My choice in meal was
Macaroni Tuna Salad, made with whole organic brown eggs. Along with other
classmates who made healthy meals, I found that eating healthy, some organic
foods was just as delicious and simple to make as the usual fast food, boxed,
and processed food that so many of us are used to.